Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OLR1Oxidized low density lipoprotein receptor 1. (360 aa)    
Predicted Functional Partners:
ROCK2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.879
APOB
Apolipoprotein B.
   
 
 0.878
ARHGEF1
Rho guanine nucleotide exchange factor 1.
     
  0.870
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.787
ARHGEF11
Rho guanine nucleotide exchange factor 11.
     
  0.704
ARHGEF12
Rho guanine nucleotide exchange factor 12.
     
  0.704
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
    
 0.615
CD36
CD36 molecule; Belongs to the CD36 family.
    
 0.598
G3TJ78_LOXAF
Uncharacterized protein.
   
 
 0.577
ISG15
ISG15 ubiquitin like modifier.
   
 0.536
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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