Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COBLUncharacterized protein. (1001 aa)    
Predicted Functional Partners:
PACSIN1
Protein kinase C and casein kinase substrate in neurons 1.
    
 
 0.945
PACSIN3
Protein kinase C and casein kinase substrate in neurons 3.
    
 
 0.936
PACSIN2
Protein kinase C and casein kinase substrate in neurons 2.
    
 
 0.935
G3TTM9_LOXAF
Cobl domain-containing protein.
 
    
 0.906
MMAB
Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
      
 0.720
ITPRID2
ITPR interacting domain containing 2.
      
 0.601
GRB10
Growth factor receptor bound protein 10.
      
 0.546
MORN5
MORN repeat containing 5.
    
 
 0.527
TMOD3
Tropomodulin 3.
    
 
 0.522
TMOD2
Tropomodulin 2.
    
 
 0.522
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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