Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F8A1Uncharacterized protein. (375 aa)    
Predicted Functional Partners:
HTT
Huntingtin.
    
 
 0.850
RAB30
RAB30, member RAS oncogene family.
    
   0.663
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
      
 0.436
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
      
 0.419
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
      
 0.419
C1orf43
Chromosome 1 open reading frame 43.
      
 0.418
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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