| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DUS2 | TRIT1 | ENSLAFP00000012223 | ENSLAFP00000014150 | Dihydrouridine synthase 2. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 0.541 |
| DUS2 | TRMT112 | ENSLAFP00000012223 | ENSLAFP00000020851 | Dihydrouridine synthase 2. | tRNA methyltransferase subunit 11-2. | 0.411 |
| DUS2 | TRMT5 | ENSLAFP00000012223 | ENSLAFP00000003018 | Dihydrouridine synthase 2. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.731 |
| DUS2 | TRMT6 | ENSLAFP00000012223 | ENSLAFP00000018589 | Dihydrouridine synthase 2. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.461 |
| FLAD1 | TRMT5 | ENSLAFP00000014966 | ENSLAFP00000003018 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.776 |
| FTSJ1 | G3TPT4_LOXAF | ENSLAFP00000026102 | ENSLAFP00000017466 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | Flavodoxin-like domain-containing protein. | 0.568 |
| FTSJ1 | LCMT2 | ENSLAFP00000026102 | ENSLAFP00000022759 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | Leucine carboxyl methyltransferase 2. | 0.564 |
| FTSJ1 | TRIT1 | ENSLAFP00000026102 | ENSLAFP00000014150 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 0.849 |
| FTSJ1 | TRMT112 | ENSLAFP00000026102 | ENSLAFP00000020851 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA methyltransferase subunit 11-2. | 0.605 |
| FTSJ1 | TRMT12 | ENSLAFP00000026102 | ENSLAFP00000010465 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA methyltransferase 12 homolog. | 0.524 |
| FTSJ1 | TRMT5 | ENSLAFP00000026102 | ENSLAFP00000003018 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.712 |
| FTSJ1 | TRMT6 | ENSLAFP00000026102 | ENSLAFP00000018589 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.859 |
| FTSJ1 | TYW3 | ENSLAFP00000026102 | ENSLAFP00000009497 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA-yW synthesizing protein 3 homolog. | 0.614 |
| G3TPT4_LOXAF | FTSJ1 | ENSLAFP00000017466 | ENSLAFP00000026102 | Flavodoxin-like domain-containing protein. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.568 |
| G3TPT4_LOXAF | LCMT2 | ENSLAFP00000017466 | ENSLAFP00000022759 | Flavodoxin-like domain-containing protein. | Leucine carboxyl methyltransferase 2. | 0.735 |
| G3TPT4_LOXAF | TRMT12 | ENSLAFP00000017466 | ENSLAFP00000010465 | Flavodoxin-like domain-containing protein. | tRNA methyltransferase 12 homolog. | 0.764 |
| G3TPT4_LOXAF | TRMT5 | ENSLAFP00000017466 | ENSLAFP00000003018 | Flavodoxin-like domain-containing protein. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.751 |
| G3TPT4_LOXAF | TYW3 | ENSLAFP00000017466 | ENSLAFP00000009497 | Flavodoxin-like domain-containing protein. | tRNA-yW synthesizing protein 3 homolog. | 0.803 |
| LCMT2 | FTSJ1 | ENSLAFP00000022759 | ENSLAFP00000026102 | Leucine carboxyl methyltransferase 2. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.564 |
| LCMT2 | G3TPT4_LOXAF | ENSLAFP00000022759 | ENSLAFP00000017466 | Leucine carboxyl methyltransferase 2. | Flavodoxin-like domain-containing protein. | 0.735 |