STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (408 aa)    
Predicted Functional Partners:
EIF4A1
Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family.
   
 0.991
G3UCD3_LOXAF
Uncharacterized protein.
   
 0.991
EIF4A3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
   
 0.984
EIF4E
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
   
 0.975
EIF4G3
Eukaryotic translation initiation factor 4 gamma 3.
   
 0.967
PDCD4
Programmed cell death 4.
   
 
 0.916
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1.
   
 0.896
PAIP1
Poly(A) binding protein interacting protein 1.
   
 0.896
EIF3I
Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
   
 
 0.894
EIF4H
Eukaryotic translation initiation factor 4H.
   
 0.894
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.