STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLCN7Chloride channel protein. (810 aa)    
Predicted Functional Partners:
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
   
 0.998
TCIRG1
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
 
 0.812
ATP6V1A
ATPase H+ transporting V1 subunit A.
   
  
 0.720
CLNS1A
Chloride nucleotide-sensitive channel 1A.
      
 0.706
TRIM47
Tripartite motif containing 47.
     
 0.703
PLEKHM1
Pleckstrin homology and RUN domain containing M1.
      
 0.691
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
   
  
 0.670
TEPSIN
TEPSIN adaptor related protein complex 4 accessory protein.
      
 0.618
CUNH19orf54
Uncharacterized protein.
      
 0.584
AVPR2
Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
      
 0.579
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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