STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A1BGAlpha-1-B glycoprotein. (500 aa)    
Predicted Functional Partners:
HPX
Hemopexin.
   
 
 0.932
G3T7Q0_LOXAF
Uncharacterized protein.
   
  
 0.868
G3T2H2_LOXAF
Uncharacterized protein.
   
 
 0.813
CLU
Clusterin; Belongs to the clusterin family.
     
 0.704
G3TGU5_LOXAF
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
 0.673
FGA
Fibrinogen alpha chain.
   
 
 0.616
CLUL1
CLb domain-containing protein.
     
 0.593
AMBP
Alpha-1-microglobulin/bikunin precursor.
   
 
 0.590
GC
GC vitamin D binding protein.
   
  
 0.585
AHSG
Alpha 2-HS glycoprotein.
   
 0.581
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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