Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF170Ring finger protein 170. (261 aa)    
Predicted Functional Partners:
TMUB1
Transmembrane and ubiquitin like domain containing 1.
    
 
 0.921
ERLIN1
ER lipid raft associated 1.
    
 
 0.913
ERLIN2
ER lipid raft associated 2.
    
 
 0.912
C6orf120
Chromosome 6 open reading frame 120.
      
 0.735
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
    
 
 0.709
TMUB2
Transmembrane and ubiquitin like domain containing 2.
    
 
 0.613
HERPUD2
HERPUD family member 2.
      
 0.611
SLC25A27
Solute carrier family 25 member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.588
PPP1R26
PPP1R26_N domain-containing protein.
      
 0.588
TMEM134
Uncharacterized protein.
      
 0.588
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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