Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SNX25Sorting nexin 25. (642 aa)    
Predicted Functional Partners:
CCDC177
Coiled-coil domain containing 177.
     
 0.738
ANKRD10
Ankyrin repeat domain 10.
    
 
 0.641
VAPB
VAMP associated protein B and C.
    
 
 0.553
RAB33A
RAB33A, member RAS oncogene family.
      
 0.545
PMS1
PMS1 homolog 1, mismatch repair system component.
   
  
 0.528
SNX14
Sorting nexin 14.
   
 
 0.518
BEND6
BEN domain containing 6.
      
 0.503
RAPGEF2
Rap guanine nucleotide exchange factor 2.
      
 0.499
RNMT
mRNA cap guanine-N7 methyltransferase.
      
 0.495
SNAPC3
Small nuclear RNA activating complex polypeptide 3.
      
 0.492
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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