Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF4TNF receptor superfamily member 4. (265 aa)    
Predicted Functional Partners:
TNFSF4
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
 0.997
TNFRSF9
TNF receptor superfamily member 9.
   
 
 0.731
TRAF1
TNF receptor-associated factor.
   
 
 0.714
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 
 0.714
G3T1U1_LOXAF
TNFR-Cys domain-containing protein.
   
  
 0.693
ICOS
Inducible T cell costimulator.
   
  
 0.677
TRAF5
TNF receptor-associated factor.
   
 
 0.658
IL2RA
Interleukin 2 receptor subunit alpha.
   
  
 0.647
CD27
CD27 molecule.
      
 0.644
TNFRSF1A
TNF receptor superfamily member 1A.
      
 0.632
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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