Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIAA1109KIAA1109. (4968 aa)    
Predicted Functional Partners:
ADAD1
Adenosine deaminase domain containing 1.
 
    
 0.823
C1orf43
Chromosome 1 open reading frame 43.
    
 
 0.793
CCDC28A
Uncharacterized protein.
    
   0.698
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1.
   
   0.607
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
   
 
 0.597
MRGBP
MRG domain binding protein.
    
   0.564
ARHGEF19
Rho guanine nucleotide exchange factor 19.
      
 0.540
KIAA0100
KIAA0100.
   
  
 0.536
PUS7
Pseudouridine synthase 7.
      
 0.534
ALS2CL
ALS2 C-terminal like.
    
 
 0.510
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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