STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCD3ATP binding cassette subfamily D member 3. (650 aa)    
Predicted Functional Partners:
PEX19
Uncharacterized protein.
    
 0.923
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 
 0.919
PEX3
Peroxisomal biogenesis factor 3.
   
 0.860
PEX13
Peroxisomal biogenesis factor 13.
   
 
 0.831
PEX16
Peroxisomal membrane protein PEX16.
     
 0.831
PEX12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
   
 
 0.800
SLC25A17
Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 
 0.753
PEX14
Peroxisomal biogenesis factor 14.
   
 0.750
ATAD1
ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.
     
 0.725
ABCD1
ATP binding cassette subfamily D member 1.
  
0.724
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.