OSGEP protein (Loxodonta africana) - STRING interaction network

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OSGEP

Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (335 aa)

Predicted Functional Partners:

TP53RK

0.995

LAGE3

0.995

TPRKB

0.993

TBC1D23

0.839

YRDC

0.832

NUP43

0.828

HYKK

0.790

TRMT2B

0.760

TRMT12

0.734

G3UH47_LOXAF

0.693

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3UH47_LOXAF	OSGEP	ENSLAFP00000027155	ENSLAFP00000003115	Uncharacterized protein.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.693
HYKK	LAGE3	ENSLAFP00000017432	ENSLAFP00000013462	Hydroxylysine kinase.	L antigen family member 3.	0.581
HYKK	OSGEP	ENSLAFP00000017432	ENSLAFP00000003115	Hydroxylysine kinase.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.790
LAGE3	HYKK	ENSLAFP00000013462	ENSLAFP00000017432	L antigen family member 3.	Hydroxylysine kinase.	0.581
LAGE3	NUP43	ENSLAFP00000013462	ENSLAFP00000010376	L antigen family member 3.	Nucleoporin 43.	0.927
LAGE3	OSGEP	ENSLAFP00000013462	ENSLAFP00000003115	L antigen family member 3.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.995
LAGE3	TP53RK	ENSLAFP00000013462	ENSLAFP00000002050	L antigen family member 3.	TP53 regulating kinase.	0.992
LAGE3	TPRKB	ENSLAFP00000013462	ENSLAFP00000021081	L antigen family member 3.	TP53RK binding protein; Belongs to the CGI121/TPRKB family.	0.981
LAGE3	YRDC	ENSLAFP00000013462	ENSLAFP00000014721	L antigen family member 3.	YrdC N6-threonylcarbamoyltransferase domain containing.	0.498
NUP43	LAGE3	ENSLAFP00000010376	ENSLAFP00000013462	Nucleoporin 43.	L antigen family member 3.	0.927
NUP43	OSGEP	ENSLAFP00000010376	ENSLAFP00000003115	Nucleoporin 43.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.828
NUP43	TP53RK	ENSLAFP00000010376	ENSLAFP00000002050	Nucleoporin 43.	TP53 regulating kinase.	0.927
NUP43	TPRKB	ENSLAFP00000010376	ENSLAFP00000021081	Nucleoporin 43.	TP53RK binding protein; Belongs to the CGI121/TPRKB family.	0.927
OSGEP	G3UH47_LOXAF	ENSLAFP00000003115	ENSLAFP00000027155	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Uncharacterized protein.	0.693
OSGEP	HYKK	ENSLAFP00000003115	ENSLAFP00000017432	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Hydroxylysine kinase.	0.790
OSGEP	LAGE3	ENSLAFP00000003115	ENSLAFP00000013462	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	L antigen family member 3.	0.995
OSGEP	NUP43	ENSLAFP00000003115	ENSLAFP00000010376	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Nucleoporin 43.	0.828
OSGEP	TBC1D23	ENSLAFP00000003115	ENSLAFP00000002844	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	TBC1 domain family member 23.	0.839
OSGEP	TP53RK	ENSLAFP00000003115	ENSLAFP00000002050	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	TP53 regulating kinase.	0.995
OSGEP	TPRKB	ENSLAFP00000003115	ENSLAFP00000021081	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	TP53RK binding protein; Belongs to the CGI121/TPRKB family.	0.993

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