Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)    
Predicted Functional Partners:
APRT
Adenine phosphoribosyltransferase.
  
 
 0.969
ADA
Adenosine deaminase.
  
 
 0.968
HPRT1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.961
GDA
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
 
 0.959
ADK
Adenosine kinase.
  
 
 0.948
NAPRT
NAPRTase_C domain-containing protein.
    
 0.938
NMRK2
Nicotinamide riboside kinase 2.
  
 0.931
NMRK1
Nicotinamide riboside kinase 1.
  
 0.931
XDH
Xanthine dehydrogenase.
   
 
 0.921
ADA2
Adenosine deaminase 2.
  
 
 0.913
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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