Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (405 aa)    
Predicted Functional Partners:
ENAH
ENAH actin regulator.
    
 0.990
VASP
Vasodilator stimulated phosphoprotein.
    
 0.990
G3TH21_LOXAF
Ras-associating domain-containing protein.
    
 0.891
APBB1IP
Uncharacterized protein.
    
 0.891
BAIAP2
BAI1 associated protein 2.
    
 0.822
CDC42
Uncharacterized protein.
   
 0.814
PFN4
Profilin; Belongs to the profilin family.
   
 0.781
ABL2
Tyrosine-protein kinase.
    
 0.758
ABL1
Tyrosine-protein kinase.
    
 0.758
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 0.726
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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