STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PGGT1BProtein geranylgeranyltransferase type I subunit beta. (378 aa)    
Predicted Functional Partners:
FNTA
Farnesyltransferase, CAAX box, alpha.
    
 0.999
CCDC112
Coiled-coil domain containing 112.
 
  
 
 0.731
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
    
 
 0.717
AMMECR1L
AMMECR1 like.
    
   0.685
AMMECR1
AMMECR1 domain-containing protein.
    
   0.685
HEY1
Hes related family bHLH transcription factor with YRPW motif 1.
    
 
 0.575
HEY2
Hes related family bHLH transcription factor with YRPW motif 2.
    
 
 0.575
HEYL
Hes related family bHLH transcription factor with YRPW motif like.
    
 
 0.575
GGPS1
Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
      
 0.545
ENY2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]
      
 0.501
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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