STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PCSK7Proprotein convertase subtilisin/kexin type 7. (775 aa)    
Predicted Functional Partners:
BSND
Barttin CLCNK type accessory beta subunit.
      
 0.888
LDLR
Low density lipoprotein receptor.
      
 0.799
PCSK9
Proprotein convertase subtilisin/kexin type 9.
      
 0.698
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.676
LIPG
Lipase G, endothelial type.
    
 0.622
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
    
 
 0.603
MBTPS1
Membrane bound transcription factor peptidase, site 1.
      
 0.580
SCG5
Secretogranin V.
   
 
 0.575
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.507
FREM1
FRAS1 related extracellular matrix 1.
    
  0.503
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.