HDAC6 protein (Loxodonta africana) - STRING interaction network

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HDAC6

Histone deacetylase 6. (1122 aa)

Predicted Functional Partners:

VCP

0.978

SQSTM1

0.944

TARDBP

0.917

G3SS82_LOXAF

0.911

CTTN

0.911

EP300

0.898

MACROH2A1

0.896

MACROH2A2

0.896

SIRT2

0.879

CFTR

0.877

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFTR	G3SS82_LOXAF	ENSLAFP00000004825	ENSLAFP00000002795	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Uncharacterized protein.	0.440
CFTR	HDAC6	ENSLAFP00000004825	ENSLAFP00000003196	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Histone deacetylase 6.	0.877
CFTR	SQSTM1	ENSLAFP00000004825	ENSLAFP00000027151	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sequestosome 1.	0.520
CFTR	TARDBP	ENSLAFP00000004825	ENSLAFP00000012078	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	TAR DNA binding protein.	0.469
CFTR	VCP	ENSLAFP00000004825	ENSLAFP00000006129	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Valosin containing protein; Belongs to the AAA ATPase family.	0.935
CTTN	HDAC6	ENSLAFP00000014019	ENSLAFP00000003196	Cortactin.	Histone deacetylase 6.	0.911
EP300	HDAC6	ENSLAFP00000010281	ENSLAFP00000003196	E1A binding protein p300.	Histone deacetylase 6.	0.898
EP300	SIRT2	ENSLAFP00000010281	ENSLAFP00000017245	E1A binding protein p300.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.879
G3SS82_LOXAF	CFTR	ENSLAFP00000002795	ENSLAFP00000004825	Uncharacterized protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.440
G3SS82_LOXAF	HDAC6	ENSLAFP00000002795	ENSLAFP00000003196	Uncharacterized protein.	Histone deacetylase 6.	0.911
G3SS82_LOXAF	SQSTM1	ENSLAFP00000002795	ENSLAFP00000027151	Uncharacterized protein.	Sequestosome 1.	0.953
G3SS82_LOXAF	TARDBP	ENSLAFP00000002795	ENSLAFP00000012078	Uncharacterized protein.	TAR DNA binding protein.	0.985
G3SS82_LOXAF	VCP	ENSLAFP00000002795	ENSLAFP00000006129	Uncharacterized protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.866
HDAC6	CFTR	ENSLAFP00000003196	ENSLAFP00000004825	Histone deacetylase 6.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.877
HDAC6	CTTN	ENSLAFP00000003196	ENSLAFP00000014019	Histone deacetylase 6.	Cortactin.	0.911
HDAC6	EP300	ENSLAFP00000003196	ENSLAFP00000010281	Histone deacetylase 6.	E1A binding protein p300.	0.898
HDAC6	G3SS82_LOXAF	ENSLAFP00000003196	ENSLAFP00000002795	Histone deacetylase 6.	Uncharacterized protein.	0.911
HDAC6	MACROH2A1	ENSLAFP00000003196	ENSLAFP00000006231	Histone deacetylase 6.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.896
HDAC6	MACROH2A2	ENSLAFP00000003196	ENSLAFP00000019979	Histone deacetylase 6.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.896
HDAC6	SIRT2	ENSLAFP00000003196	ENSLAFP00000017245	Histone deacetylase 6.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.879

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