STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERASES cell expressed Ras. (228 aa)    
Predicted Functional Partners:
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.922
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.917
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.917
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.908
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
   
 0.908
RGL1
Ral guanine nucleotide dissociation stimulator like 1.
   
 0.905
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.898
RASA1
RAS p21 protein activator 1.
   
 0.896
RALBP1
RalA binding protein 1.
    
 0.893
RASSF5
Ras association domain family member 5.
    
 0.889
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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