Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDH18Uncharacterized protein. (333 aa)    
Predicted Functional Partners:
G3T1F0_LOXAF
CA domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins.
 
   
  0.937
CTNNA2
Uncharacterized protein.
   
 0.635
CTNNA2-2
Uncharacterized protein.
   
 0.635
CTNNA1
Catenin alpha 1.
   
 0.635
CDH2
Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.
  
  
 
0.559
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
  
  
 
0.559
APC2
APC regulator of WNT signaling pathway 2.
     
 0.548
APC
APC regulator of WNT signaling pathway.
     
 0.548
CDH11
Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins.
  
  
 
0.544
CDH10
Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins.
  
  
 
0.543
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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