Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADGRE2Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (691 aa)    
Predicted Functional Partners:
CD55
Uncharacterized protein.
   
 0.631
IZUMO1
Izumo sperm-egg fusion 1.
      
 0.480
TCN1
Transcobalamin 1.
      
 0.479
MAN2B1-2
Alpha-mannosidase.
    
 
 0.478
MAN2B1
Alpha-mann_mid domain-containing protein.
    
 
 0.478
S100A2
Protein S100; Belongs to the S-100 family.
      
 0.462
CCDC54
Coiled-coil domain containing 54.
      
 0.461
SPAM1
Uncharacterized protein.
      
 0.460
CRISP2
Cysteine rich secretory protein 2; Belongs to the CRISP family.
   
  
 0.456
GNB2
G protein subunit beta 2.
   
 0.431
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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