STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELZHelicase with zinc finger. (1944 aa)    
Predicted Functional Partners:
CNOT1
CCR4-NOT transcription complex subunit 1.
   
 
 0.664
RC3H2
Ring finger and CCCH-type domains 2.
   
 
 0.641
SMYD2
SET and MYND domain containing 2.
    
 0.583
ATXN2L
Ataxin 2 like.
   
 
 0.572
PITPNC1
Phosphatidylinositol transfer protein cytoplasmic 1.
      
 0.553
PHF3
PHD finger protein 3.
   
  
 0.549
KMT2E
Lysine methyltransferase 2E.
   
 
 0.474
GTF2E2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
      
 0.452
DEAF1
DEAF1 transcription factor.
      
 0.445
NKX2-8
NK2 homeobox 8.
      
 0.443
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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