STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RHBDF1Rhomboid 5 homolog 1. (857 aa)    
Predicted Functional Partners:
ADAM17
ADAM metallopeptidase domain 17.
    
 0.963
FRMD8
FERM domain containing 8.
     
 0.850
RHBDF2
Rhomboid 5 homolog 2.
     
  0.762
MEGF11
Multiple EGF like domains 11.
   
  
 0.721
WSCD2
WSC domain containing 2.
   
  
 0.717
NPRL3
NPR3 like, GATOR1 complex subunit.
      
 0.673
REEP1
Receptor expression-enhancing protein.
      
 0.646
ADAM10
ADAM metallopeptidase domain 10.
    
 0.645
IGF2BP2
Insulin like growth factor 2 mRNA binding protein 2.
      
 0.623
MPZL3
Myelin protein zero like 3.
      
 0.614
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.