Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGFBITransforming growth factor beta induced. (682 aa)    
Predicted Functional Partners:
FN1
Fibronectin 1.
   
 
 0.691
NRN1
Neuritin 1.
      
 0.599
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
      
 0.575
MT-ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
    
 0.539
CAPG
Capping actin protein, gelsolin like.
   
 
 0.526
ITIH1
Inter-alpha-trypsin inhibitor heavy chain 1.
   
  
 0.516
ANPEP
Aminopeptidase.
   
  
 0.509
PLIN1
Perilipin; Belongs to the perilipin family.
   
 
 0.485
SERPINF1
Serpin family F member 1; Belongs to the serpin family.
   
  
 0.481
COL6A2
Collagen type VI alpha 2 chain.
   
 
 0.465
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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