Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RAP1GDS1Rap1 GTPase-GDP dissociation stimulator 1. (628 aa)    
Predicted Functional Partners:
RASL10A
RAS like family 10 member A.
    
  0.813
DENND4A
DENN domain containing 4A.
      
 0.737
RAC2
Rac family small GTPase 2.
    
  0.670
RAC1
Rac family small GTPase 1.
    
  0.670
PLEKHB1
Pleckstrin homology domain containing B1.
    
 
 0.666
DNAL1
Dynein axonemal light chain 1.
    
   0.661
FBXL4
F-box and leucine rich repeat protein 4.
      
 0.654
STPG2
Sperm tail PG-rich repeat containing 2.
      
 0.626
RASL10B
RAS like family 10 member B.
    
  0.620
RHOB
Ras homolog family member B.
    
 0.575
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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