STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP2Matrix metallopeptidase 2. (665 aa)    
Predicted Functional Partners:
MMP9
Matrix metallopeptidase 9.
   
 0.841
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.836
MMP1
Matrix metallopeptidase 1.
   
 0.834
MMP14
Matrix metallopeptidase 14.
   
 0.820
VEGFA
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
     
 0.791
THBS1
Thrombospondin 1.
   
 0.790
HBEGF
Heparin binding EGF like growth factor.
    
 0.779
EDN1
Endothelin 1.
     
 0.778
SRC
Tyrosine-protein kinase.
    
 0.774
CYBB
Cytochrome b-245 beta chain.
   
 
 0.773
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.