STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP2Matrix metallopeptidase 2. (665 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.947
MMP14
Matrix metallopeptidase 14.
  
0.944
MMP1
Matrix metallopeptidase 1.
   
 
0.941
MMP9
Matrix metallopeptidase 9.
  
0.934
HBEGF
Heparin binding EGF like growth factor.
    
 0.929
THBS1
Thrombospondin 1.
   
 0.917
EDN1
Endothelin 1.
     
 0.912
SRC
Tyrosine-protein kinase.
    
 0.910
VEGFA
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
     
 0.908
CYBB
Cytochrome b-245 beta chain.
   
 
 0.906
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.