Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PROM1Prominin 1. (781 aa)    
Predicted Functional Partners:
G3SMI1_LOXAF
Uncharacterized protein.
      
 0.737
CD34
CD34 molecule.
      
 0.734
CD44
CD44 molecule (Indian blood group).
      
 0.649
NES
Nestin; Belongs to the intermediate filament family.
      
 0.643
CD24
Uncharacterized protein.
      
 0.642
NANOG
Homeobox domain-containing protein.
      
 0.617
TSG101
Tumor susceptibility 101.
    
 
 0.608
PECAM1
Platelet and endothelial cell adhesion molecule 1.
  
   
 0.606
EPCAM
Epithelial cell adhesion molecule.
   
  
 0.600
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
      
 0.596
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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