Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRUNE1Prune exopolyphosphatase 1. (451 aa)    
Predicted Functional Partners:
PRUNE2
CRAL-TRIO domain-containing protein.
 
   
 0.961
BNIP2
BCL2 interacting protein 2.
 
 
  
 0.928
HDDC3
HD domain containing 3.
     
 0.872
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.798
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 
 0.786
GSK3A
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.786
NME1
Nucleoside diphosphate kinase.
  
 
 0.653
APRT
Adenine phosphoribosyltransferase.
     
 0.580
UTP20
UTP20 small subunit processome component.
      
 0.562
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component.
      
 0.545
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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