STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GABPB2GA binding protein transcription factor subunit beta 2. (413 aa)    
Predicted Functional Partners:
GABPA
Uncharacterized protein.
   
 0.813
G3U7V7_LOXAF
Uncharacterized protein.
   
 0.813
CASP2
Caspase 2; Belongs to the peptidase C14A family.
    
  0.520
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
    
  0.501
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
    
   0.485
G3T747_LOXAF
ANK_REP_REGION domain-containing protein.
  
     0.481
CDKN2C
Cyclin dependent kinase inhibitor 2C.
  
     0.464
CDKN2D
Cyclin dependent kinase inhibitor 2D.
  
     0.454
SMIM7
Small integral membrane protein 7.
     
 0.429
IFT81
Intraflagellar transport 81.
    
 0.423
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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