Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MYRFMyelin regulatory factor. (1086 aa)    
Predicted Functional Partners:
G3T0K9_LOXAF
Uncharacterized protein.
      
 0.737
SPO11
SPO11 initiator of meiotic double stranded breaks.
    
 
 0.707
RFFL
RING-type domain-containing protein.
      
 0.690
PDGFRA
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
      
 0.670
SOX10
SRY-box transcription factor 10.
      
 0.653
ICK
Intestinal cell kinase.
    
 0.639
MAK
Male germ cell associated kinase.
    
 0.639
MOK
MOK protein kinase; Belongs to the protein kinase superfamily.
    
 0.639
MOG
Myelin oligodendrocyte glycoprotein.
   
 
 0.625
ERMN
Ermin.
   
  
 0.594
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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