Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FKBP11Peptidylprolyl isomerase. (198 aa)    
Predicted Functional Partners:
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
 
 0.806
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.733
OST4
Oligosaccharyltransferase complex subunit 4, non-catalytic.
   
 
 0.667
STT3A
STT3 oligosaccharyltransferase complex catalytic subunit A.
   
 
 0.662
SSR4
Signal sequence receptor subunit 4.
   
 
 0.652
RPL38
Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.
   
 
 0.639
DDOST
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
   
 
 0.635
SEC61G
SEC61 translocon gamma subunit.
   
 
 0.626
SSR1
Signal sequence receptor subunit 1.
   
 
 0.626
G3U7E9_LOXAF
Uncharacterized protein.
   
 
 0.620
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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