STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKD1NKD inhibitor of WNT signaling pathway 1. (470 aa)    
Predicted Functional Partners:
DVL1
Dishevelled segment polarity protein 1.
    
 0.933
DVL3
Dishevelled segment polarity protein 3.
    
 0.917
DVL2
Dishevelled segment polarity protein 2.
    
 0.917
G3TVD3_LOXAF
EF-hand domain-containing protein.
     
  0.812
ADCY7
Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
  
 0.562
RSPRY1
Ring finger and SPRY domain containing 1.
      
 0.542
TENT4A
Terminal nucleotidyltransferase 4A.
      
 0.542
GPATCH3
G-patch domain containing 3.
      
 0.538
AXIN2
Axin 2.
   
  
 0.534
SNX20
Sorting nexin 20.
      
 0.531
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.