| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | ASS1 | ENSLAFP00000013424 | ENSLAFP00000000871 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Argininosuccinate synthase 1. | 0.824 |
| ALDH18A1 | OAT | ENSLAFP00000013424 | ENSLAFP00000021976 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.975 |
| ALDH18A1 | OTC | ENSLAFP00000013424 | ENSLAFP00000008309 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.725 |
| ALDH18A1 | PM20D1 | ENSLAFP00000013424 | ENSLAFP00000003547 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Peptidase M20 domain containing 1. | 0.791 |
| ALDH18A1 | PSAT1 | ENSLAFP00000013424 | ENSLAFP00000015019 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Phosphoserine aminotransferase. | 0.855 |
| ASS1 | ALDH18A1 | ENSLAFP00000000871 | ENSLAFP00000013424 | Argininosuccinate synthase 1. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.824 |
| ASS1 | DPYD | ENSLAFP00000000871 | ENSLAFP00000001505 | Argininosuccinate synthase 1. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.428 |
| ASS1 | OAT | ENSLAFP00000000871 | ENSLAFP00000021976 | Argininosuccinate synthase 1. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.986 |
| ASS1 | OTC | ENSLAFP00000000871 | ENSLAFP00000008309 | Argininosuccinate synthase 1. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.999 |
| ASS1 | PM20D1 | ENSLAFP00000000871 | ENSLAFP00000003547 | Argininosuccinate synthase 1. | Peptidase M20 domain containing 1. | 0.802 |
| ASS1 | PSAT1 | ENSLAFP00000000871 | ENSLAFP00000015019 | Argininosuccinate synthase 1. | Phosphoserine aminotransferase. | 0.782 |
| CPQ | PM20D1 | ENSLAFP00000015600 | ENSLAFP00000003547 | Carboxypeptidase Q. | Peptidase M20 domain containing 1. | 0.577 |
| DHODH | DPYD | ENSLAFP00000022356 | ENSLAFP00000001505 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.526 |
| DHODH | OAT | ENSLAFP00000022356 | ENSLAFP00000021976 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.455 |
| DHODH | PM20D1 | ENSLAFP00000022356 | ENSLAFP00000003547 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Peptidase M20 domain containing 1. | 0.620 |
| DHODH | PSAT1 | ENSLAFP00000022356 | ENSLAFP00000015019 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Phosphoserine aminotransferase. | 0.455 |
| DPYD | ASS1 | ENSLAFP00000001505 | ENSLAFP00000000871 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Argininosuccinate synthase 1. | 0.428 |
| DPYD | DHODH | ENSLAFP00000001505 | ENSLAFP00000022356 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.526 |
| DPYD | OAT | ENSLAFP00000001505 | ENSLAFP00000021976 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.462 |
| DPYD | PM20D1 | ENSLAFP00000001505 | ENSLAFP00000003547 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Peptidase M20 domain containing 1. | 0.620 |