Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PM20D1Peptidase M20 domain containing 1. (511 aa)    
Predicted Functional Partners:
OTC
Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
 
 0.757
ASS1
Argininosuccinate synthase 1.
  
 0.744
NUCKS1
Nuclear casein kinase and cyclin dependent kinase substrate 1.
      
 0.721
SLC41A1
Solute carrier family 41 member 1.
      
 0.719
RAB29
RAB29, member RAS oncogene family.
      
 0.713
GK5
Glycerol kinase 5; Belongs to the FGGY kinase family.
   
  
 0.676
AGMAT
Agmatinase; Belongs to the arginase family.
  
 
 0.668
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.611
G3TGW9_LOXAF
Kazal-like domain-containing protein.
      
 0.570
ARG2
Arginase.
  
 
 0.553
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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