Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TXNDC16Thioredoxin domain containing 16. (822 aa)    
Predicted Functional Partners:
FOXRED2
FAD dependent oxidoreductase domain containing 2.
    
 
 0.858
SUOX
Sulfite oxidase.
    
 0.837
VDAC2
Voltage dependent anion channel 2.
   
 
 0.746
FLNA
Filamin A.
    
   0.734
NIPAL2
NIPA like domain containing 2.
      
 0.684
STXBP4
Syntaxin binding protein 4.
      
 0.646
KHK
Ketohexokinase.
   
  
 0.621
STYX
Serine/threonine/tyrosine interacting protein.
     
 0.610
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.591
RTRAF
RNA transcription, translation and transport factor.
      
 0.561
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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