SLC9A3R2 protein (Loxodonta africana) - STRING interaction network

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SLC9A3R2

Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (337 aa)

Predicted Functional Partners:

EZR

0.980

CFTR

0.972

MSN

0.932

RDX

0.926

PODXL

0.921

LPAR2

0.841

SGK1

0.835

PHLPP1

0.807

PHLPP2

0.793

SUOX

0.790

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFTR	EZR	ENSLAFP00000004825	ENSLAFP00000007813	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Ezrin.	0.717
CFTR	RDX	ENSLAFP00000004825	ENSLAFP00000012502	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Radixin.	0.401
CFTR	SLC9A3R2	ENSLAFP00000004825	ENSLAFP00000003566	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.972
CFTR	SUOX	ENSLAFP00000004825	ENSLAFP00000006911	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sulfite oxidase.	0.483
EZR	CFTR	ENSLAFP00000007813	ENSLAFP00000004825	Ezrin.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.717
EZR	MSN	ENSLAFP00000007813	ENSLAFP00000023158	Ezrin.	Moesin.	0.999
EZR	PODXL	ENSLAFP00000007813	ENSLAFP00000014961	Ezrin.	Uncharacterized protein.	0.593
EZR	RDX	ENSLAFP00000007813	ENSLAFP00000012502	Ezrin.	Radixin.	0.999
EZR	SLC9A3R2	ENSLAFP00000007813	ENSLAFP00000003566	Ezrin.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.980
LPAR2	SLC9A3R2	ENSLAFP00000007033	ENSLAFP00000003566	Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.841
MSN	EZR	ENSLAFP00000023158	ENSLAFP00000007813	Moesin.	Ezrin.	0.999
MSN	RDX	ENSLAFP00000023158	ENSLAFP00000012502	Moesin.	Radixin.	0.999
MSN	SLC9A3R2	ENSLAFP00000023158	ENSLAFP00000003566	Moesin.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.932
PHLPP1	PHLPP2	ENSLAFP00000008582	ENSLAFP00000006459	PH domain and leucine rich repeat protein phosphatase 1.	PH domain and leucine rich repeat protein phosphatase 2.	0.973
PHLPP1	SGK1	ENSLAFP00000008582	ENSLAFP00000010620	PH domain and leucine rich repeat protein phosphatase 1.	Non-specific serine/threonine protein kinase.	0.504
PHLPP1	SLC9A3R2	ENSLAFP00000008582	ENSLAFP00000003566	PH domain and leucine rich repeat protein phosphatase 1.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.807
PHLPP2	PHLPP1	ENSLAFP00000006459	ENSLAFP00000008582	PH domain and leucine rich repeat protein phosphatase 2.	PH domain and leucine rich repeat protein phosphatase 1.	0.973
PHLPP2	SGK1	ENSLAFP00000006459	ENSLAFP00000010620	PH domain and leucine rich repeat protein phosphatase 2.	Non-specific serine/threonine protein kinase.	0.405
PHLPP2	SLC9A3R2	ENSLAFP00000006459	ENSLAFP00000003566	PH domain and leucine rich repeat protein phosphatase 2.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.793
PODXL	EZR	ENSLAFP00000014961	ENSLAFP00000007813	Uncharacterized protein.	Ezrin.	0.593

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