STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIITAClass II major histocompatibility complex transactivator. (1150 aa)    
Predicted Functional Partners:
RFX5
Regulatory factor X5.
    
 
 0.851
RFXANK
Regulatory factor X associated ankyrin containing protein.
   
 
 0.748
RFXAP
Regulatory factor X associated protein.
      
 0.694
RFX1
Regulatory factor X1.
    
 
 0.620
NWD1
NACHT and WD repeat domain containing 1.
   
  
 0.568
CD74
CD74 molecule.
   
  
 0.552
NLRX1
NLR family member X1.
      
 0.540
CREB1
cAMP responsive element binding protein 1.
   
  
 0.537
BIRC7
Baculoviral IAP repeat containing 7.
    
 0.493
HLA-DMA
Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.
   
  
 0.480
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.