Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CIITAClass II major histocompatibility complex transactivator. (1150 aa)    
Predicted Functional Partners:
RFX5
Regulatory factor X5.
    
 0.992
RFXANK
Regulatory factor X associated ankyrin containing protein.
   
 0.985
RFXAP
Regulatory factor X associated protein.
     
 0.960
STAT1
Signal transducer and activator of transcription.
   
 0.941
NFYA
Nuclear transcription factor Y subunit alpha.
     
 0.910
NFYC
Nuclear transcription factor Y subunit gamma.
     
 0.909
NFYB
Nuclear transcription factor Y subunit beta.
     
 0.908
CREB1
cAMP responsive element binding protein 1.
     
 0.887
CEBPB
BZIP domain-containing protein.
     
 0.872
CEBPG
CCAAT enhancer binding protein gamma.
     
  0.870
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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