Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM47Tripartite motif containing 47. (636 aa)    
Predicted Functional Partners:
DDX58
DExD/H-box helicase 58.
   
 0.882
CLCN7
Chloride channel protein.
     
 0.703
AVPR2
Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
      
 0.700
UBE2L6
Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.622
NLRP3
NLR family pyrin domain containing 3.
    
 0.590
IFIH1
Interferon induced with helicase C domain 1.
   
 0.586
MGAM
Maltase-glucoamylase.
      
 0.574
MAVS
Mitochondrial antiviral signaling protein.
   
 0.570
ZC3HAV1
Zinc finger CCCH-type containing, antiviral 1.
   
 0.561
LOC100676713
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.527
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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