STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (957 aa)    
Predicted Functional Partners:
ARID4A
AT-rich interaction domain 4A.
    
 0.804
ARID4B
AT-rich interaction domain 4B.
    
 0.804
KAT5
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.749
NCOR1
Nuclear receptor corepressor 1.
    
 0.730
MEF2A
Myocyte enhancer factor 2A.
   
 
 0.719
NCOR2
Nuclear receptor corepressor 2.
    
 0.682
FOXA1
Forkhead box A1.
    
 0.679
EP300
E1A binding protein p300.
    
 0.656
SIN3B
SIN3 transcription regulator family member B.
   
 0.638
SIN3A
SIN3 transcription regulator family member A.
   
 0.638
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (32%) [HD]