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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHOQRas homolog family member Q. (205 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.992
G3U095_LOXAF
Uncharacterized protein.
    
 0.992
CRK
CRK proto-oncogene, adaptor protein.
   
 
 0.954
CRKL
CRK like proto-oncogene, adaptor protein.
   
 
 0.937
ITSN1
Intersectin 1.
    
 0.908
GOPC
PDZ domain-containing protein.
    
 0.840
EXOC7
Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
    
 0.810
CDC42EP3
CDC42 effector protein 3.
    
 0.739
CDC42EP4
CDC42 effector protein 4.
    
 0.735
CDC42EP2
CDC42 effector protein 2.
    
 0.714
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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