STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB37Zinc finger and BTB domain containing 37. (503 aa)    
Predicted Functional Partners:
DARS2
Aspartyl-tRNA synthetase 2, mitochondrial.
 
    
 0.767
FER
Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
    
 0.587
GAS2
Growth arrest specific 2.
    
 0.542
MAP4K3
Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
      
 0.524
ANKRD45
ANK_REP_REGION domain-containing protein.
    
 
 0.478
CNN1
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
    
 
 0.442
SGK1
Non-specific serine/threonine protein kinase.
    
 0.438
CENPL
Centromere protein L.
   
 0.430
SMG7
SMG7 nonsense mediated mRNA decay factor.
    
 
 0.422
RPS5
Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
    
 0.416
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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