STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAS2Growth arrest specific 2. (314 aa)    
Predicted Functional Partners:
CASP7
Caspase 7; Belongs to the peptidase C14A family.
    
 0.733
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.732
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
      
 0.670
CENPU
Uncharacterized protein.
    
 0.580
G3UFD7_LOXAF
Uncharacterized protein.
    
 0.580
ZBTB37
Zinc finger and BTB domain containing 37.
    
 0.542
G3TI52_LOXAF
Uncharacterized protein.
      
 0.541
CASP14
Caspase 14; Belongs to the peptidase C14A family.
    
 0.529
G3UKH5_LOXAF
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.529
ENY2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]
    
 0.500
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.