STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (261 aa)    
Predicted Functional Partners:
SLC4A1
Anion exchange protein.
   
 
 0.873
GUCA2A
Guanylate cyclase activator 2A.
   
  
 0.796
CABIN1
Calcineurin binding protein 1.
   
  
 0.741
REV1
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.
      
 0.700
STK40
Serine/threonine kinase 40.
      
 0.662
CA13
Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family.
   
 
 0.631
CA1
Carbonic anhydrase 1; Belongs to the alpha-carbonic anhydrase family.
   
 
 0.631
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
      
 0.623
SERINC5
Serine incorporator 5.
      
 0.623
TCIRG1
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.606
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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