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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEP1BMeprin A subunit. (703 aa)    
Predicted Functional Partners:
PRCP
Prolylcarboxypeptidase.
     
 0.924
MME
Membrane metalloendopeptidase.
     
 0.917
MEP1A
Meprin A subunit.
  
 
 
0.915
XPNPEP2
X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.
   
 0.914
ACE2
Angiotensin-converting enzyme.
   
 
 0.913
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
     
 0.909
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
   
 
 0.550
GM2A
GM2 ganglioside activator.
      
 0.534
FETUB
Fetuin B.
    
 
 0.442
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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