Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (470 aa)    
Predicted Functional Partners:
ID1
Inhibitor of DNA binding 1, HLH protein.
     
 0.944
SRF
Serum response factor.
    
 0.908
ETS1
ETS proto-oncogene 1, transcription factor.
   
 0.892
MAPK1
Mitogen-activated protein kinase.
    
 0.853
MAPK3
Mitogen-activated protein kinase.
    
 0.853
CDK10
Cyclin dependent kinase 10; Belongs to the protein kinase superfamily.
    
 
 0.816
CREBBP
CREB binding protein.
   
 
 0.810
ELK4
ETS transcription factor ELK4.
   
 
 0.787
EP300
E1A binding protein p300.
   
 
 0.786
ELK1
ETS transcription factor ELK1.
     
  0.762
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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