Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPB42Erythrocyte membrane protein band 4.2. (691 aa)    
Predicted Functional Partners:
SLC4A1
Anion exchange protein.
   
 0.997
AHSP
Alpha hemoglobin stabilizing protein.
   
  
 0.967
RHAG
Rh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
   
 0.949
TMOD1
Tropomodulin 1.
   
  
 0.847
SPTA1
Spectrin alpha, erythrocytic 1.
   
 
 0.843
SPTB
Spectrin beta chain; Belongs to the spectrin family.
   
 
 0.788
DMTN
Dematin actin binding protein.
   
  
 0.758
FN1
Fibronectin 1.
    
 0.729
HBQ1
Hemoglobin subunit theta 1; Belongs to the globin family.
   
  
 0.727
STRADB
STE20 related adaptor beta.
   
  
 0.721
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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