STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NDC80NDC80 kinetochore complex component. (645 aa)    
Predicted Functional Partners:
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.999
SPC25
SPC25 component of NDC80 kinetochore complex.
   
 0.999
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.999
SPC24
Uncharacterized protein.
   
 0.999
DSN1
DSN1 component of MIS12 kinetochore complex.
   
 0.997
BUB1B
Uncharacterized protein.
   
 0.995
NSL1
NSL1 component of MIS12 kinetochore complex.
   
 0.994
MIS12
MIS12 kinetochore complex component.
   
 0.993
TTK
TTK protein kinase.
   
 
 0.989
ZWINT
ZW10 interacting kinetochore protein.
   
 0.987
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.