Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
SPENSpen family transcriptional repressor. (3666 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.993
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.951
NCOR2
Nuclear receptor corepressor 2.
   
 
 0.881
NCOR1
Nuclear receptor corepressor 1.
   
 
 0.764
WTAP
WT1 associated protein.
    
 
 0.707
RAN
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
    
   0.665
PHF3
PHD finger protein 3.
   
  
 0.596
CHD4
Uncharacterized protein.
   
   0.572
VIRMA
Vir like m6A methyltransferase associated.
   
 
 0.565
EP300
E1A binding protein p300.
   
  
 0.560
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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