Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (758 aa)    
Predicted Functional Partners:
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
  
0.999
NFKBIA
NFKB inhibitor alpha.
    
 0.997
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.996
RELA
RELA proto-oncogene, NF-kB subunit.
    
 0.996
TNFRSF1A
TNF receptor superfamily member 1A.
   
 0.995
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.995
RIPK1
Receptor interacting serine/threonine kinase 1.
   
0.993
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
   
 0.993
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
   
 0.991
NFKBIB
NFKB inhibitor beta.
    
 0.989
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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