Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC6Leucine rich repeat containing 6. (472 aa)    
Predicted Functional Partners:
ZMYND10
Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.
     
 0.835
SPAG1
Sperm associated antigen 1.
    
 0.767
DNAI2
Dynein axonemal intermediate chain 2.
    
 0.756
DNAI1
Dynein axonemal intermediate chain 1.
    
 0.756
DNALI1
Dynein axonemal light intermediate chain 1.
   
 0.756
CCDC39
Coiled-coil domain containing 39.
   
 0.751
CCDC40
Coiled-coil domain containing 40.
   
 
 0.747
RSPH9
Radial spoke head 9 homolog.
    
 
 0.723
ARMC4
Armadillo repeat containing 4.
   
 
 0.719
DNAAF4
Dynein axonemal assembly factor 4.
    
 0.714
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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