Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COPS7ACOP9 signalosome subunit 7A. (275 aa)    
Predicted Functional Partners:
COPS4
COP9 signalosome subunit 4.
   
 0.995
COPS3
COP9 signalosome subunit 3.
    
 0.994
GPS1
G protein pathway suppressor 1.
  
 0.993
COPS8
COP9 signalosome subunit 8.
    
 0.992
COPS6
COP9 signalosome subunit 6.
   
 0.991
COPS2
COP9 signalosome subunit 2.
    
 0.991
COPS7B
COP9 signalosome subunit 7B.
  
0.984
DDB2
Damage specific DNA binding protein 2.
    
 0.968
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.960
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.956
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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